Living in Greenville, I can wholly attest to that. Virtually everyone in this hospital and town, when traveling, flies out of RDU. Since moving here in mid 2004, I have flown out of RDU x 25, PGV (Greenville) x2, ISO (Kinston) x 2. Rarely does it make economic sense to fly out of the local airports. I have never heard of anyone flying out of Norfolk, Myrtle Beach, or Wilmington (2 lane roads and traffic lights are no fun)
RDU is served by Southwest, jetBlue, Airtran, Continental, Northwest, US Airways, Delta, American, United, Air Canada. I have never heard of Southern Skyways and Myrtle Direct Air. What sort of operations do they do? Sounds interesting.