I haven't thought the whole thing through. I guess I would mean doing what Greenville did decades ago and choosing to make Main St. a "destination" for people and not just a functional street. I walked up and down Main St. the other day--there are some vacant street-level properties that I would love to see new businesses open up in. As for ambitious "redevelopment" I would consider offering buyouts of some of the older stores on Main St. that may not be frequented that often but are able to stay because they've been there for decades don't have the same overhead as other stores. I would just like to see more restaurants, more popular shopping options, coffee houses, bars, eateries, public spaces, etc. There are some areas on Main St. that can be made into small public parks too.
I have not studied the Downtown Master Plan--this may address some of what I have described. But I generally feal that there is a reluctance by folks on the Eastside/the "old money" community to move Spartanburg's downtown into looking more like a downtown Greenville. I say this as someone who has lived on the Westside for 20 years and also think of downtown as part of my city.