I don't mean to dig up a dead topic but I figured I should throw in my two cents.
I was born in raised in the Palm Beach County Area. I attended college at FSU in Tallahassee. So I have seen both sides of the issue.
I think that it is less that South Florida -Central Florida also- is very different that Tallahassee, but that Tallahassee is very different that the rest of the state. Compared to the rest of the Florida, Tallahassee is very isolated.
Most of the people in the south go from major metro to major metro with out any thought. For example, when I lived in West Palm Beach, I attended a concert in Ft. Lauderdale. There was no major planning involved; you just have to leave a bit earlier. I believe it is a similar thing with Tampa/Orlando.
In Tallahassee, the closest major metro is about 3 hours away. Visiting Pensacola/Jacksonville is a major undertaking that takes all day. Also, there is little or no urban development between Tallahasse and the other major metros. Just a whole crap load of trees. In addition, I also noticed that many Tallahassee residents visit other states when they go on vacation. They rarely if ever go futher south than Disney World (this is from what I have seen. take it as you will).
Basically, many people in Tallahassee don't experience the rest of Florida. You would think that the elected representatives from the South and Central Florida would help with the gap between the capital and the rest of the state, but I don't see that happening.
Things are changing though. If you look at the Tallahassee forum, you see a lot of new projects and ideas coming to fruitation. However you also see many of the posters frustrated by backwards local governments and NIMBY residents.
The idea of making South Florida it's own state is a nice idea, but that would be like cutting off your face because your nose is stuffed up. I think the rest of Florida just needs to poke at the capital a bit and try to work together. I think it would work much better than everyone trading names with each other.
That was alot more than two cents. Hopefully I didn't piss anyone off.